Festival: Manchester Science Festival, various venues, Manchester, until October 31 2010
Founded in 2007, the vibrant MSF aims to seize the science heritage of the city and encourage innovators of the future, laying on more than 200 events across the Mancunian metropolis this year.
It's a chance to turn your drawings or photos into sound and hear the result on a BBC big screen in Exchange Square, have a crack at periscopes at the Imperial War Museum North and pose life's big questions to the Punk Science team at The Comedy Store.
Enhance your knowledge of Vedic mathematics and Indus archaeology at the Manchester Museum or branch out to the likes of Bury Art Gallery and Museum and the Lowry in Salford, which hosts a one-woman show on Dorothy Hodgkin, Britain's only female Nobel prizewinner in science.
There are also a range of more unusual venues to massage your grey matter in, including pubs, churches, universities and climbing centres.
See our previews of Manchester Science Festival week at the Museum of Science and Industry and Manchester Metropolitan University.
Visit www.manchestersciencefestival.com or the festival blog for full details.